4.8 stars - based on 31 reviews

iS Clinical

Pro-Heal Serum Advance+


"Some of my clients with sensitive skin find vitamin C to be irritating—but not this one. It calms redness, blemishes, and inflammation while delivering all the benefits of vitamin C: brightness, a more even skin tone, and powerful antioxidant protection."

Ideal for those with dry, sensitive, and inflamed skin, iS Clinical Pro Heal Serum Advance+ helps soothe redness and blemishes while minimizing the appearance of fine lines, wrinkles and other signs of aging. Its cushiony, antioxidant-rich formula—featuring an advanced, highly stable form of vitamin C along with vitamins E and A—also helps protect skin from future damage due to the sun and other environmental factors.

Size: 1 fl oz / 30 ml

Please Note: This product is only available to ship within the United States at this time.

Retinol Reform

Complimentary Retinol Reform & Intensive Eye Cream Minis w/ any $150 order.


How to Use

In the AM after cleansing, apply 3-4 drops of serum—or enough to smooth over face and neck. Follow with moisturizer and sunscreen.

Formulated Without

  • Parabens
  • Silicone
  • Dimethicone

Key Ingredients

L-Ascorbic Acid:

A scientifically-advanced, highly stable form of vitamin C, which helps to calm and protect against the visual effects of UV damage.

Vitamin E:

A highly effective antioxidant that helps minimize inflammation and protect against the visual effects of UV damage.

Retinol (Vitamin A):

A powerful antioxidant that helps minimize the appearance of fine lines, wrinkles, and other signs of aging.

Olive Leaf Extract:

A anti-acne, antioxidant extract that helps support blemish-prone and aging skin.


For best results, apply this serum in the morning—its antioxidants will help defend your skin from environmental stressors like UV rays and pollution. (Just don’t forget to top it off with sunscreen!)


A favorite of Shani’s A-list clients, iS Clinical is known for its physician-grade, plant-powered formulas that target acne and signs of aging.
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