4.8 stars - based on 33 reviews

iS Clinical

Active Serum

$ 138

"I always recommend this serum for those with blemish-prone skin who are also trying to minimize signs of aging. This formula helps to gently exfoliate for clearer, brighter skin."

IS Clinical’s most popular product, Active Serum helps decrease fine lines and wrinkles, minimizes the appearance of pores, evens skin tone, and is excellent for blemish-prone skin. It provides both rapid and long-term noticeable results.

Size: 1 fl oz

PLEASE NOTE: This product is only available to ship within the United States at this time.

Receive a complimentary deluxe Cleansing Serum with your $125 purchase.

How to Use

Can be used the AM and/or PM, after cleanser and toner, apply a fuller dropper or enough to smooth over face and neck. The tingling sensation is completely normal and should dissipate in a few minutes.

Formulated Without
  • Parabens
  • Silicone
  • Dimethicone
Key Ingredients

Sugar Cane Extract:

Source of Glycolic Acid which gently exfoliates the skin for a renewed complexion.

Bilberry Extract:

Source of Lactic Acid, a natural exfoliant with moisturizing properties

White Willow Bark Extract:

Source of Salicylic Acid, this exfoliates the skin and deep-cleanses pores.

Arbutin & Mushroom Extract:

Assists in minimizing the appearance of uneven skin tone while brightening the overall complexion.


I recommend alternating nights with Active Serum and Retinol Reform for blemish-prone skin.
Shop Retinol Reform


A good skincare routine combines multiple actives (like Vitamin C, Retinol and Salicylic Acid) between AM and PM for the most optimal results. The best delivery system? Potent serums that deliver targeted benefits.